A triterpene glycoside; reduces intracellular calcium concentrations

23-epi-26-Deoxyactein – 1 mg

Brand:
Cayman
CAS:
264624-38-6
Storage:
-20
UN-No:
Non-Hazardous - /

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa).{43486,43487} It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).{43486} 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.{43487}  

 

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SKU: 25126 - 1 mg Category:

Description

A triterpene glycoside; reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of ROS, and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by TCDD; reduces methylglyoxal-induced production of ROS and IL-1β and cell death in RIN-m5F β-cells from 0.01-10 μM

Formal name: (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl, β-D-xylopyranoside

Synonyms:  27-Deoxyactein

Molecular weight: 660.8

CAS: 264624-38-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Cell Biology|ECM & Adhesion Molecules||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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