Description
A biflavonoid; inhibits the proliferation of OVCAR-3 ovarian and HeLa cervical cancer cells (EC50s = 3 and 5.2 μg/ml, respectively); induces apoptosis and caspase-3 cleavage in OVCAR-3 cells at 3 μg/ml; reduces ear edema and PGE2 levels in a mouse model of PMA-induced chronic skin inflammation at 20 μg/ear applied topically; decreases the thickness of the intima-media and lipid plaque deposition in the thoracic aorta in a rat model of high-fat diet-induced atherosclerosis at 100 mg/kg; improves sensorimotor coordination and increases the time spent on a rotating bar in a mouse model of MPTP-induced Parkinson’s disease at 0.8 mg/kg per day
Formal name: 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Synonyms:
Molecular weight: 566.5
CAS: 481-46-9
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Flavonoids||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease
