A bacterial metabolite; active against five strains of P. falciparum (EC50s = 160-340 nM); not cytotoxic to HEK293 or HepG2 cell lines but is cytotoxic to Jurkat T lymphocytes (IC50 = 60 µg/ml)

Padanamide A – 5 mg

Brand:
Cayman
CAS:
1314881-80-5
Storage:
-20
UN-No:
Non-Hazardous - /

Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species.{42129} It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 µg/ml.{42130,42131}  

 

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SKU: 25085 - 5 mg Category:

Description

A bacterial metabolite; active against five strains of P. falciparum (EC50s = 160-340 nM); not cytotoxic to HEK293 or HepG2 cell lines but is cytotoxic to Jurkat T lymphocytes (IC50 = 60 µg/ml)

Formal name: (S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide

Synonyms: 

Molecular weight: 661.8

CAS: 1314881-80-5

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Parasitic Diseases|Malaria

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