A phenolic compound; scavenges DPPH (EC50 = 0.184 mg/ml) and AAPH radicals (IC50 = 0.124 mg/ml); decreases IL-6 and TNF-α serum levels and macrophage infiltration into epididymal adipose tissue in high-fat diet-fed rats at 90 mg/kg per day; decreases serum and liver FFA levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats at 90 mg/kg per day

5-Caffeoylquinic Acid – 5 mg

Brand:
Cayman
CAS:
906-33-2
Storage:
-20
UN-No:
Non-Hazardous - /

5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}  

 

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SKU: 25054 - 5 mg Category:

Description

A phenolic compound; scavenges DPPH (EC50 = 0.184 mg/ml) and AAPH radicals (IC50 = 0.124 mg/ml); decreases IL-6 and TNF-α serum levels and macrophage infiltration into epididymal adipose tissue in high-fat diet-fed rats at 90 mg/kg per day; decreases serum and liver FFA levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats at 90 mg/kg per day

Formal name: (1R,3R,4S,5R)-3-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid

Synonyms:  trans-5-O-Caffeoylquinic Acid|5-O-Caffeoylquinic Acid|Neochlorogenic Acid

Molecular weight: 354.3

CAS: 906-33-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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