An internal standard for the quantification of L-thyroxine by GC- or LC-MS

L-Thyroxine-13C9,15N – 1 mg

Brand:
Cayman
CAS:
1431868-11-9
Storage:
-20
UN-No:
Non-Hazardous - /

L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine (Item No. 14116) by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine.{43116,43117,43118} In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone (Item No. 22917) from the anterior pituitary in mice.{43116} It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism.{43117,43118} Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.  

 

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SKU: 25039 - 1 mg Category:

Description

An internal standard for the quantification of L-thyroxine by GC- or LC-MS

Formal name: O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine-carboxy,α,β,1,2,3,4,5,6-13C9-15N

Synonyms:  ​Levothyroxine-13C9,15N|L-T4-13C9,15N

Molecular weight: 786.8

CAS: 1431868-11-9

Purity: ≥98%

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|13C||Product Type|Biochemicals|Isotopically Labeled Standards|15N||Product Type|Biochemicals|Natural Products||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Thyroid Hormones

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