An internal standard for the quantification of linezolid by GC- or LC-MS

Linezolid-d3 – 1 mg

Brand:
Cayman
CAS:
1127120-38-0
Storage:
-20
UN-No:
Non-Hazardous - /

Linezolid-d3 is intended for use as an internal standard for the quantification of linezolid (Item No. 15012) by GC- or LC-MS. Linezolid is a synthetic oxazolidinone antibiotic with activity against a wide range of Gram-positive bacteria, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), penicillin-resistant pneumococci, vancomycin-resistant enterococci, various anaerobic bacteria, and several mycobacteria and streptococci (MICs = 2-4 mg/ml).{22653} Linezolid inhibits protein synthesis by binding to domain V of the 23S ribosomal RNA of the 50S subunit of bacterial ribosomes. In vivo, linezolid (50 mg/kg) reduces pulmonary MRSA load in spontaneously breathing and mechanically ventilated rabbits.{36681} Formulations containing linezolid have been used to treat MRSA infections.  

 

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SKU: 25038 - 1 mg Category:

Description

An internal standard for the quantification of linezolid by GC- or LC-MS ,

Formal name: N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide-d3

Synonyms: 

Molecular weight: 340.4

CAS: 1127120-38-0

Purity: ≥99% deuterated forms (d1-d3)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Antibiotics|Oxazolidinones||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA

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