A fluorogenic substrate for caspase-1; EDANS is released upon cleavage by caspase-1 and its fluorescence can be used to quantify caspase-1 activity; EDANS ex/em = 340/485 nm

Dabcyl-YVADAPV-EDANS – 1 mg

Brand:
Cayman
CAS:
161877-70-9
Storage:
-20
UN-No:
Non-Hazardous - /

Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1.{42039} Upon enzymatic cleavage by caspase-1, EDANS is separated from the Dabcyl quencher and can be used to quantify caspase-1 activity. EDANS displays excitation/emission maxima of 340/485 nm, respectively.  

 

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SKU: 24993 - 1 mg Category:

Description

A fluorogenic substrate for caspase-1; EDANS is released upon cleavage by caspase-1 and its fluorescence can be used to quantify caspase-1 activity; EDANS ex/em = 340/485 nm

Formal name: N-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-valinamide

Synonyms:  Dabcyl-ICE-EDANS

Molecular weight: 1,233.40

CAS: 161877-70-9

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Pyroptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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