α-Endorphin (human, mouse, rat, porcine, bovine, ovine) – 1 mg

Brand:
Cayman
CAS:
59004-96-5
Storage:
-20
UN-No:
De Minimis - 3077 / 9

α-Endorphin is an endogenous neuropeptide that binds to opioid receptors in guinea pig brain membranes (IC50 = 97 nM).{39621} It induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 nM and inhibits electrically-induced contractions in guinea pig ileum and mouse vas deferens (IC50s = 325 and 27.6 nM, respectively).{40896,39621} In vivo, α-endorphin delays extinction of pole-jumping avoidance behavior in rats (ED50s = 40 and 2 pM, respectively, for s.c. and i.c.v. administration).{39622}  

 

Available on backorder

SKU: 24958 - 1 mg Category:

Description

An endogenous neuropeptide that binds to opioid receptors in guinea pig brain membranes (IC50 = 97 nM); induces chemotaxis of human monocytes in vitro (0.1 nM); inhibits electrically-induced contractions in guinea pig ileum and mouse vas deferens (IC50s = 325 and 27.6 nM, respectively); delays extinction of pole-jumping avoidance behavior in rats (ED50s = 40 and 2 pM, respectively for s.c. and i.c.v. administration),


Formal name: L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-α-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonine

Synonyms: 

Molecular weight: 1,746.00

CAS: 59004-96-5

Purity: ≥95%

Formulation: A lyophilized powder


Product Type|Biochemicals|Peptides|Neuropeptides||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Behavioral Neuroscience