Description
A bone peptide; secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone; plasma levels increase in diseases that induce dysregulated bone turnover; positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women; induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics; positively associated with calcification of aortic tissue and heart valves in humans,
Formal name: L-tyrosyl-L-leucyl-L-tyrosyl-L-glutaminyl-L-tryptophyl-L-leucylglycyl-L-alanyl-L-prolyl-L-valyl-L-prolyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-leucyl-4-carboxy-L-α-glutamyl-L-prolyl-L-arginyl-L-arginyl-4-carboxy-L-α-glutamyl-L-valyl-L-cysteinyl-4-carboxy-L-α-glutamyl-L-leucyl-L-asparaginyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-α-aspartyl-L-α-glutamyl-L-leucyl-L-alanyl-L-α-aspartyl-L-histidyl-L-isoleucylglycyl-L-phenylalanyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-tyrosyl-L-arginyl-L-arginyl-L-phenylalanyl-L-tyrosylglycyl-L-prolyl-L-valine cyclic (23→29)-disulfide, trifluoroacetate salt
Synonyms:
Molecular weight: 5,929.40
CAS: 136461-80-8
Purity: ≥95%
Formulation: A lyophilized powder
Product Type|Biochemicals|Peptides||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Vasculature|Smooth Muscle Cells||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes
