A fluorogenic substrate for MMP-1 and MMP-9; upon cleavage by MMP-1 or MMP-9

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 – 1 mg

Brand:
Cayman
CAS:
150956-92-6
Storage:
-20
UN-No:
Non-Hazardous - /

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9.{38801} Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.  

 

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SKU: 24709 - 1 mg Category:

Description

A fluorogenic substrate for MMP-1 and MMP-9; upon cleavage by MMP-1 or MMP-9, Nma is unquenched and its fluorescence can be used to quantify MMP activity,

Formal name: 1-(2,4-dinitrophenyl)-L-prolyl-3-cyclohexyl-L-alanylglycyl-S-methyl-L-cysteinyl-L-histidyl-L-alanyl-N6-[2-(methylamino)benzoyl]-L-lysinamide

Synonyms:  Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2|Matrix Metalloproteinase-1/Matrix Metalloproteinase-9 Fluorogenic Substrate|MMP-1/MMP-9 Fluorogenic Substrate

Molecular weight: 1,077.20

CAS: 150956-92-6

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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