A fluorogenic caspase-3 substrate; upon enzymatic cleavage by caspase-3

Ac-DNLD-AMC – 1 mg

Brand:
Cayman
CAS:
958001-92-8
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.{39492} Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively.  

 

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SKU: 24566 - 1 mg Category:

Description

A fluorogenic caspase-3 substrate; upon enzymatic cleavage by caspase-3, AMC is released and its fluorescence can be used to quantify caspase-3 activity; AMC ex/em = 340-360/440-460 nm, respectively,

Formal name: N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine

Synonyms:  Ac-Asp-Asn-Leu-Asp-MCA|Caspase-3 Substrate|N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin

Molecular weight: 674.7

CAS: 958001-92-8

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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