An internal standard for the quantification of C16sphingomyelin by GC- or LC-MS

C16 Sphingomyelin-13C (d18:1/16:0-13C) – 1 mg

Brand:
Cayman
CAS:
144236-99-7
Storage:
-20
UN-No:
Non-Hazardous - /

C16 Sphingomyelin-13C (d18:1/16:0-13C) is intended for use as an internal standard for the quantification of C16sphingomyelin (Item No. 10007946) by GC- or LC-MS. C16 Sphingomyelin is a naturally occurring sphingolipid.{37418,40751,37417} Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease.{37418,40751} Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer.{37417} Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC; Item No. 15102), and cholesterol (Item No. 9003100) have been used in the study of lipid raft dynamics and membrane organization.{48564,48565}  

 

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SKU: 24452 - 1 mg Category:

Description

An internal standard for the quantification of C16sphingomyelin by GC- or LC-MS

Formal name: [R-[R*,S*-(E)]]-4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetracosan-1-aminium-9-13C, 4-oxide, inner salt

Synonyms:  N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine-13C|Palmitoyl Sphingomyelin-13C|SM(d18:1/16:0-13C)|Sphingomyelin (d18:1/16:0-13C)

Molecular weight: 704

CAS: 144236-99-7

Purity: ≥98%

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|13C||Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience

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