A bioactive sphingolipid; inhibits IL-4 production by 53.84% in EL4 T cells (10 μM); reduces the growth of human papillomavirus type 16-associated tumors in mice; reduces natural killer T cell activity

C12 Galactosylceramide (d18:1/12:0) – 5 mg

Brand:
Cayman
CAS:
41613-14-3
Storage:
-20
UN-No:
Non-Hazardous - /

C12 Galactosylceramide is a bioactive sphingolipid.{13011,41440,41441} It inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM.{13011} C12 Galactosylceramide reduces the growth of human papillomavirus type 16-associated tumors in mice and reduces tumor recurrence following surgical removal or chemotherapy.{41440} It also reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus.{41441} [Matreya, LLC. Catalog No. 1937]  

 

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SKU: 24347 - 5 mg Category:

Description

A bioactive sphingolipid; inhibits IL-4 production by 53.84% in EL4 T cells (10 μM); reduces the growth of human papillomavirus type 16-associated tumors in mice; reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus

Formal name: N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-dodecanamide

Synonyms:  Galactosylceramide (d18:1/12:0)|GalCer(d18:1/12:0)|N-dodecanoyl-β-D-Galactosylceramide

Molecular weight: 643.9

CAS: 41613-14-3

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Autoimmunity|Lupus||Research Area|Lipid Biochemistry|Sphingolipids

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