A dual inhibitor of MMP-2 and MMP-9 (IC50s = 17 and 30 nM

MMP-2/MMP-9 Inhibitor II – 1 mg

Brand:
Cayman
CAS:
193807-60-2
Storage:
-20
UN-No:
Non-Hazardous - /

MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively).{32343} In mice, it suppresses lung colonization of Lewis lung carcinoma cells and inhibits tumor-induced angiogenesis, tumor growth, and liver metastasis.{32343},{37366}  

 

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SKU: 24314 - 1 mg Category:

Description

A dual inhibitor of MMP-2 and MMP-9 (IC50s = 17 and 30 nM, respectively); suppresses lung colonization of Lewis lung carcinoma cells and inhibits tumor-induced angiogenesis, tumor growth, and liver metastasis in mice

Formal name: (αR)-α-[([1,1′-biphenyl]-4-ylsulfonyl)amino]-N-hydroxy-benzenepropanamide

Synonyms:  Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II

Molecular weight: 396.5

CAS: 193807-60-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cancer|Angiogenesis||Research Area|Cancer|Cell Migration & Metastasis

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