An S-nitrosothiol NO donor; decompensates to release NO in vitro; induces dose-dependent vasodilation of isolated

SNVP – 10 mg

Brand:
Cayman
CAS:
225233-99-8
Storage:
-20
UN-No:
Non-Hazardous - /

SNVP is an S-nitrosothiol that acts as a nitric oxide (NO) donor and vasodilator.{39649} It decompensates to release NO in vitro, an effect that is enhanced by both CuSO4 and cysteine. SNVP induces dose-dependent vasodilation of isolated, precontracted, and endothelium-intact rat arteries (pD2 = 5.74). It also induces sustained vasodilation of isolated, precontracted, and endothelium-denuded rat arteries when used at concentrations greater than 1 μM.  

 

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Description

An S-nitrosothiol NO donor; decompensates to release NO in vitro; induces dose-dependent vasodilation of isolated, precontracted, and endothelium-intact rat arteries (pD2 = 5.74); induces sustained vasodilation of isolated, precontracted, and endothelium-denuded rat arteries (>1 μM),

Formal name: 3-(nitrosothio)-N-(1-oxopentyl)-valine

Synonyms:  S-Nitroso-N-valeryl-DL-penicillamine

Molecular weight: 262.3

CAS: 225233-99-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|NO Donors||Research Area|Cardiovascular System|Vasculature|Vasodilation

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