A pyrethroid insecticide; modulates Nav channels; slowly activates recombinant rat Nav1.8 expressed in Xenopus oocytes and delays inactivation; decreases the mean burst rate in rat primary neurons (IC50 = 0.99 μM

Cyfluthrin – 100 mg

Brand:
Cayman
CAS:
68359-37-5
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).{36375,41867} It slowly activates rat recombinant Nav1.8 channels, delays inactivation by longer than 40 ms, and induces persistent tail currents in channels expressed in X. laevis oocytes.{36375} It also decreases the mean burst rate in rat primary neurons (IC50 = 0.99 μM, respectively).{41867} Cyfluthrin is toxic to various insects, including A. melinus, G. ashmeadi, E. eremicus, and E. formosa (LC50s = 7, 67, 96, and 63 ng/ml, respectively) and the A. sinensis mosquito (LC50 = 0.446 ppm).{41868,41869} It is also toxic to A. mellifera honeybees (LD50 = 0.22 ppm), affecting locomotor activity and wing fanning behavior with an increase in the mean bout duration of time spent upside down, indicating disruption of the righting reflex, and a decrease in wing fanning behavior when administered at a dose of 10 ng/bee.{41870} Formulations containing cyfluthrin have been used for the control of insects in agriculture and for non-commercial purposes.  

 

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SKU: 24231 - 100 mg Category:

Description

A pyrethroid insecticide; modulates Nav channels; slowly activates recombinant rat Nav1.8 expressed in Xenopus oocytes and delays inactivation; decreases the mean burst rate in rat primary neurons (IC50 = 0.99 μM, respectively); toxic to various insects, including A. melinus, G. ashmeadi, E. eremicus, and E. formosa (LC50s = 7, 67, 96, and 63 ng/ml, respectively) and the A. sinensis mosquito (LC50 = 0.446 ppm); toxic to A. mellifera honeybees (LD50 = 0.22 ppm), affecting locomotor activity and wing fanning behavior at 10 ng/bee

Formal name: 3-(2,2-dichloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, cyano(4-fluoro-3-phenoxyphenyl)methyl ester

Synonyms:  β-Cyfluthrin

Molecular weight: 434.3

CAS: 68359-37-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Neuroscience||Research Area|Toxicology|Environmental|Agriculture

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