A metabolite of triadimefon; induces cranial nerve and ganglia abnormalities in a rat post-implantation whole embryo culture model from 12.5-125 μM; induces embryotoxicity in rats and rabbits when administered orally at doses of 100 and 40 mg/kg respectively; induces embryonic mortality as well as decreases fertility and increases the number of female offspring in medaka fish (O. latipes) from 3-3

Triadimenol – 250 mg

Brand:
Cayman
CAS:
55219-65-3
Storage:
-20
UN-No:
Non-Hazardous - /

Triadimenol is a metabolite of triadimefon (Item No. 18714), a broad-spectrum chiral triazole fungicide, that is formed by reduction of a carbonyl group to the corresponding alcohol.{42231} It is teratogenic, inducing cranial nerve and ganglia abnormalities in a rat post-implantation whole embryo culture model when used at concentrations ranging from 12.5 to 125 μM.{42232} In vivo, triadimenol induces embryotoxicity in rats and rabbits when administered orally at doses of 100 and 40 mg/kg, respectively. Embryonic exposure to triadimenol (3-3,000 μg/L) induces embryonic mortality as well as decreases fertility and increases the number of female offspring in medaka fish (O. latipes).{42233}  

 

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Description

A metabolite of triadimefon; induces cranial nerve and ganglia abnormalities in a rat post-implantation whole embryo culture model from 12.5-125 μM; induces embryotoxicity in rats and rabbits when administered orally at doses of 100 and 40 mg/kg respectively; induces embryonic mortality as well as decreases fertility and increases the number of female offspring in medaka fish (O. latipes) from 3-3,000 μg/L,

Formal name: β-(4-chlorophenoxy)-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol

Synonyms: 

Molecular weight: 295.8

CAS: 55219-65-3

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Neuroscience||Research Area|Toxicology|Drug Metabolism|Drug Metabolites||Research Area|Toxicology|Environmental

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