A depsidone; an inhibitor of PPDK (IC50 = 42.3 µM); inhibits the growth of C4

Unguinol – 1 mg

Brand:
Cayman
CAS:
36587-59-4
Storage:
-20
UN-No:
Non-Hazardous - /

Unguinol is a depsidone originally isolated from A. unguis.{37787} It is an inhibitor of pyruvate phosphate dikinase (PPDK; IC50 = 42.3 µM).{37788} It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s = 8.7 and 69.5 µM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s = 28.2, 50.8, and 44.3 µM, respectively).  

 

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SKU: 24207 - 1 mg Category:

Description

A depsidone; an inhibitor of PPDK (IC50 = 42.3 µM); inhibits the growth of C4, but not C3 plants; inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s = 8.7 and 69.5 µM, respectively); inhibits the growth of H460, MCF-7, and SF-268 cancer cells (GI50s = 28.2, 50.8, and 44.3 µM, respectively)

Formal name: 3,8-dihydroxy-1,9-dimethyl-6-[(1E)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one

Synonyms: 

Molecular weight: 326.3

CAS: 36587-59-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Plant Biology|Plant Growth Regulators

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