A peptide hormone; produced from proglucagon in pancreatic α cells; stimulates glucose production ex vivo in isolated rat hepatocytes; stimulates glucose output from perfused rat livers via increases in gluconeogenesis and glycogenolysis and decreases in glycolysis; increases plasma glucose levels in rats; secretion is suppressed in response to food intake in normal rats and humans but is maintained or elevated in humans with type 2 diabetes

Glucagon – 1 mg

Brand:
Cayman
CAS:
16941-32-5
Storage:
-20
UN-No:
Non-Hazardous - /

Glucagon is a peptide hormone produced from proglucagon in pancreatic α cells that has a role in the regulation of glucose metabolism.{41561} Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo.{41562} It also stimulates glucose output from perfused rat livers via increases in gluconeogenesis and glycogenolysis and decreases in glycolysis as well as increases plasma glucose levels in rats.{41561,41563} Glucagon secretion is suppressed in response to food intake in normal rats and humans but is maintained or elevated in humans with type 2 diabetes.{41561}  

 

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SKU: 24204 - 1 mg Category:

Description

A peptide hormone; produced from proglucagon in pancreatic α cells; stimulates glucose production ex vivo in isolated rat hepatocytes; stimulates glucose output from perfused rat livers via increases in gluconeogenesis and glycogenolysis and decreases in glycolysis; increases plasma glucose levels in rats; secretion is suppressed in response to food intake in normal rats and humans but is maintained or elevated in humans with type 2 diabetes

Formal name: glucagon (swine)

Synonyms: 

Molecular weight: 3,482.80

CAS: 16941-32-5

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Peptides|Peptide Hormones||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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