A fungal metabolite; has antibiotic activity against Gram-positive (S. aureus) and Gram-negative (V. cholerae and S. flexneri) bacteria; MICs = 64 µg/ml for V. cholerae and S. flexneri; selectively cytotoxic to cancerous cells over non-cancerous cells (LC50s = 9.21 and 261.14 µg/ml for HeLa and Vero cells

Citromycetin – 1 mg

Brand:
Cayman
CAS:
478-60-4
Storage:
-20
UN-No:
Non-Hazardous - /

Citromycetin is a fungal metabolite originally isolated from P. frequentans with antibiotic activity against the Gram-positive bacteria S. aureus and the Gram-negative bacteria V. cholerae and S. flexneri (MICs = 64 µg/ml for both).{41375,41376} Citromycetin is selectively cytotoxic to cancerous cells over non-cancerous cells (LC50s = 9.21 and 261.14 µg/ml for HeLa and Vero cells, respectively). Formulations containing citromycetin have been studied for use in the treatment of amyloidosis and α-synuclein fibril diseases.{41374}  

 

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SKU: 24175 - 1 mg Category:

Description

A fungal metabolite; has antibiotic activity against Gram-positive (S. aureus) and Gram-negative (V. cholerae and S. flexneri) bacteria; MICs = 64 µg/ml for V. cholerae and S. flexneri; selectively cytotoxic to cancerous cells over non-cancerous cells (LC50s = 9.21 and 261.14 µg/ml for HeLa and Vero cells, respectively)

Formal name: 8,9-dihydroxy-2-methyl-4-oxo-4H,5H-pyrano[3,2-c][1]benzopyran-10-carboxylic acid

Synonyms:  NSC 53584

Molecular weight: 290.2

CAS: 478-60-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Cholera||Research Area|Infectious Disease|Bacterial Diseases|Food-borne Illnesses||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease

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