A peptide hormone with vasoconstrictive and antidiuretic activities; binds to V1 receptors (Kd = 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes

Argipressin – 1 mg

Brand:
Cayman
CAS:
113-79-1
Storage:
-20
UN-No:
Non-Hazardous - /

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.{38625,38626} It also stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM).{38623} In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.{38624,38622}  

 

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SKU: 24154 - 1 mg Category:

Description

A peptide hormone with vasoconstrictive and antidiuretic activities; binds to V1 receptors (Kd = 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively); stimulates intracellular Ca2+ release in A7r5 cells (EC50 = 5 nM); induces hypertension and tachycardia when injected into the lateral septal nuclei (100-400 ng); increases heart rate and MAP when injected into the medial amygdaloid body (150-600 ng)

Formal name: 8-L-arginine-vasopressin

Synonyms:  [Arg8]-Vasopressin|AVP

Molecular weight: 1,084.20

CAS: 113-79-1

Purity: ≥95%

Formulation: A lyophilized powder

Product Type|Biochemicals|Peptides|Neuropeptides||Product Type|Biochemicals|Peptides|Peptide Hormones||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Cardiovascular System|Vasculature|Vasoconstriction

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