An insecticide; a selective antagonist of insect GABA receptors (IC50s = 30 and 1

Fipronil – 100 mg

Brand:
Cayman
CAS:
120068-37-3
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively).{41694} It also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.{41695} Formulations containing fipronil have been used as insecticides in veterinary care.  

 

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SKU: 24128 - 100 mg Category:

Description

An insecticide; a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively); inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 and 10 nM, respectively); induces CYP1A1/2, CYP2B1/2, and CYP3A1/2 activity in isolated rat liver microsomes

Formal name: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile

Synonyms: 

Molecular weight: 437.1

CAS: 120068-37-3

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Pesticides||Product Type|Biochemicals|Small Molecule Activators||Research Area|Neuroscience||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Environmental

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