Lipoxin B4 methyl ester – 50 µg

Brand:
Cayman
CAS:
97589-07-6
Storage:
-80
UN-No:
De Minimis - 1170 / 3

Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 (Item No. 90420). LXB4 is a positional isomer of LXA4 (Item No. 90410) produced by the metabolism of 15-HETE (Item No. 34700) or 15-HpETE (Item No. 44720) by human leukocytes.{369,350} At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.{16457}  

 

Available on backorder

SKU: 24073 - 50 µg Category:

Description

A lipid soluble prodrug of LXB4


Formal name: 5S,14R,15S-trihydroxy-6E,8Z,10E,12E-eicosatetraenoic acid, methyl ester

Synonyms:  LXB4 methyl ester

Molecular weight: 366.5

CAS: 97589-07-6

Purity: ≥95%

Formulation: A solution in ethanol


Product Type|Biochemicals|Lipids|Lipoxins/Resolvin Es||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Sterol Lipids