An internal standard for the quantification of AGN 193109 by GC- or LC-MS

AGN 193109-d7 – 1 mg

Brand:
Cayman
CAS:
1216429-25-2
Storage:
-20
UN-No:
Non-Hazardous - /

AGN 193109-d7 is intended for use as an internal standard for the quantification of AGN 193109 (Item No. 23975) by GC- or LC-MS. AGN 193109 is an antagonist of retinoic acid receptors (RARs).{41300} AGN 193109 decreases expression of cytokeratin K5-8, 13, 14, 16, 17, and 19 genes, markers of retinoid action in ECE16-1 cells, when co-administered with TTNPB (Item No. 16144) but not when used alone. In vivo, AGN 193109 induces cleft palate or frontonasal dysplasia and eye malformations in fetuses of pregnant mice following a single oral dose of 1 mg/kg.{41301}     

 

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SKU: 23976 - 1 mg Category:

Description

An internal standard for the quantification of AGN 193109 by GC- or LC-MS

Formal name: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl-d7)-2-naphthalenyl]ethynyl]-benzoic acid

Synonyms: 

Molecular weight: 399.5

CAS: 1216429-25-2

Purity: ≥99% deuterated forms (d1-d7).

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area

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