An anticonvulsant; decreases the levels of α-oxoglutarate

Trimethadione – 50 mg

Brand:
Cayman
CAS:
127-48-0
Storage:
-20
UN-No:
Non-Hazardous - /

Trimethadione is an anticonvulsant.{36303,38543} It decreases the levels of α-oxoglutarate, malate, and fumarate in the brain as well as plasma glucose levels in rats.{36303} Trimethadione increases latency to first pentetrazole-induced clonic seizure in mice (ED50 = 10 mg/kg).{38543} It also inhibits absence-like seizures but not tonic convulsions in spontaneously epileptic rats.{38544}  

 

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SKU: 23893 - 50 mg Category:

Description

An anticonvulsant; decreases the levels of α-oxoglutarate, malate, and fumarate in the brain, as well as plasma glucose levels in rats; increases latency to first pentetrazole-induced clonic seizure in mice (ED50 = 10 mg/kg); inhibits absence-like seizures but not tonic convulsions in spontaneously epileptic rats,

Formal name: 3,5,5-trimethyl-2,4-oxazolidinedione

Synonyms:  NSC 15799|NSC 169503

Molecular weight: 143.1

CAS: 127-48-0

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals||Research Area|Neuroscience|Seizure Disorders

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