A peptide linker molecule; used in the synthesis of antibody-drug conjugates

Mc-Val-Cit-PABC-PNP – 5 mg

Brand:
Cayman
CAS:
159857-81-5
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs).{37316} It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin (Item No. 15007) or monomethyl auristatin E (MMAE; Item No. 16267).{37316,37315} ADCs target specific cell populations to induce a selective response, such as cell death in cancer cells.  

 

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SKU: 23881 - 5 mg Category:

Description

A peptide linker molecule; used in the synthesis of antibody-drug conjugates

Formal name: N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-L-ornithinamide

Synonyms:  Maleimidocaproyl-L-Valine-L-Citrulline-p-Aminobenzyl Alcohol p-Nitrophenyl Carbonate

Molecular weight: 737.8

CAS: 159857-81-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Synthetic Intermediates & Building Blocks||Research Area|Cancer|Cell Death

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