A fungal metabolite; has antibacterial activity at a concentration of 1 mg/ml; more cytotoxic

Aspochalasin D – 5 mg

Brand:
Cayman
CAS:
71968-02-0
Storage:
-20
UN-No:
Non-Hazardous - /

Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that was initially thought to be inactive.{38485} It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.{38484} Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s = 0.49 and 1.9 µg/ml, respectively).{38486}  

 

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SKU: 23864 - 5 mg Category:

Description

A fungal metabolite; has antibacterial activity at a concentration of 1 mg/ml; more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s = 0.49 and 1.9 µg/ml, respectively)

Formal name: (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,15(2H)-dione

Synonyms: 

Molecular weight: 401.5

CAS: 71968-02-0

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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