A prodrug of ethynyl estradiol; demethylated in the liver to ethynyl estradiol; has weak estrogenic properties

Mestranol – 10 mg

Brand:
Cayman
CAS:
72-33-3
Storage:
-20
UN-No:
Non-Hazardous - /

Mestranol is a semi-synthetic estrogen prodrug of ethynyl estradiol (Item No. 10006486), an estrogen receptor agonist.{41236} It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response.{41237} Formulations containing mestranol were previously used as oral contraceptives.  

 

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SKU: 23822 - 10 mg Category:

Description

A prodrug of ethynyl estradiol; demethylated in the liver to ethynyl estradiol; has weak estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal

Formal name: 3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17α-ol

Synonyms:  EE 3-ME|Ethynyl Estradiol 3-methyl ether|NSC 84032|SC-475|Δ-MVE

Molecular weight: 310.4

CAS: 72-33-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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