An antiviral active against lipid envelope-containing viruses (ID50s = 3-12 nM for inhibition of replication); inhibits HSV-1 replication and protein synthesis and HSV-2 plaque formation and virus production in vitro; inhibits the HSV envelope from fusing with the plasma membrane

Docosanol – 250 g

Brand:
Cayman
CAS:
661-19-8
Storage:
4
UN-No:
Non-Hazardous - /

Docosanol is an aliphatic alcohol that has broad-spectrum antiviral activity against viruses with a lipid envelope (ID50s = 3-12 nM for inhibition of replication).{41277} It inhibits herpes simplex virus type 1 (HSV-1) replication and protein synthesis in Vero cells.{41276} It also inhibits HSV-2 plaque formation and virus production in wild-type Vero cells and cells resistant to acyclovir (Item No. 14160). Docosanol acts by prohibiting the HSV envelope from fusing with the plasma membrane.{41277} Formulations containing docosanol have been used in the topical treatment of HSV-1.  

 

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SKU: 23793 - 250 g Category:

Description

An antiviral active against lipid envelope-containing viruses (ID50s = 3-12 nM for inhibition of replication); inhibits HSV-1 replication and protein synthesis and HSV-2 plaque formation and virus production in vitro; inhibits the HSV envelope from fusing with the plasma membrane

Formal name: 1-docosanol

Synonyms:  n-Docosanol|Behenyl Alcohol|Docosyl Alcohol|NSC 8407

Molecular weight: 326.6

CAS: 661-19-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Entry/fusion Inhibitors||Product Type|Biochemicals|Lipids|Docosanoids||Product Type|Biochemicals|Lipids|Fatty Alcohols/Aldehydes||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HSV

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