A synthetic glucocorticoid (Ki = 78 pM for the glucocorticoid receptor); increases intraocular pressure in sheep following ocular administration of a 0.05% w/v solution

Difluprednate – 25 mg

Brand:
Cayman
CAS:
23674-86-4
Storage:
-20
UN-No:
Non-Hazardous - /

Difluprednate is a synthetic glucocorticoid that potently activates the glucocorticoid receptor (Ki = 78 pM).{41345} In vivo, ocular administration of difluprednate (0.05% w/v) increases intraocular pressure in sheep.{41346} Formulations containing difluprednate have been used to treat diabetic macular edema and inflammation following cataract surgery.  

 

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SKU: 23776 - 25 mg Category:

Description

A synthetic glucocorticoid (Ki = 78 pM for the glucocorticoid receptor); increases intraocular pressure in sheep following ocular administration of a 0.05% w/v solution,

Formal name: 21-(acetyloxy)-6α,9-difluoro-11β-hydroxy-17-(1-oxobutoxy)-pregna-1,4-diene-3,20-dione

Synonyms:  W-6309

Molecular weight: 508.6

CAS: 23674-86-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Ophthalmology

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