A depsidone with antibacterial activity; inhibits the growth of MRSA (MIC = 2 µg/ml); has larvicidal activity against Artemia (LC50 = 1.7 µg/ml); has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 µM)

Nornidulin – 5 mg

Brand:
Cayman
CAS:
33403-37-1
Storage:
-20
UN-No:
Non-Hazardous - /

Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini.{38475} It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 2 µg/ml) and has larvicidal activity toward Artemia (LC50 = 1.7 µg/ml).{38476} Nornidulin has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 µM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >116.4 µM).{38477}  

 

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SKU: 23646 - 5 mg Category:

Description

A depsidone with antibacterial activity; inhibits the growth of MRSA (MIC = 2 µg/ml); has larvicidal activity against Artemia (LC50 = 1.7 µg/ml); has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 µM)

Formal name: 2,4,7-trichloro-3,8-dihydroxy-1,9-dimethyl-6-(1-methyl-1-propen-1-yl)-11H-dibenzo[b,e][1,4]dioxepin-11-one

Synonyms: 

Molecular weight: 429.7

CAS: 33403-37-1

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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