A perylenequinone that has diverse biological activities; inhibits the growth of chloroquine-sensitive and -resistant P. falciparum strains (IC50s = 2.75 and 1.94 μM for D6 and W2 clones

Diacetylcercosporin – 1 mg

Brand:
Cayman
CAS:
62574-06-5
Storage:
-20
UN-No:
Non-Hazardous - /

Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities.{41238} It inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine (Item No. 14194; IC50s = 2.75 and 1.94 μM for D6 and W2 clones, respectively) and L. donovani parasites (IC50 = 3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SK-OV-3 human cancer cell lines (IC50s = 4.8-8.7 μM). It is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM  

 

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SKU: 23639 - 1 mg Category:

Description

A perylenequinone that has diverse biological activities; inhibits the growth of chloroquine-sensitive and -resistant P. falciparum strains (IC50s = 2.75 and 1.94 μM for D6 and W2 clones, respectively); inhibits growth of L. donovani parasites (IC50 = 3.1 μM); exhibits cytotoxicity against SK-MEL, KB, BT549, and SK-OV-3 human cancer cell lines (IC50s = 4.8-8.7 μM); a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM

Formal name: [S-(R*,R*)]-8,9-bis[2-(acetyloxy)propyl]-5,12-dihydroxy-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-6,11-dione

Synonyms: 

Molecular weight: 618.6

CAS: 62574-06-5

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Plant Biology|Phytotoxins||Research Area|Plant Biology|Plant Growth Regulators

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