Description
An aminoglycoside antibiotic; effective against Gram-negative and Gram-positive bacteria (MICs = 0.08-3.9 µg/ml); antiprotozoal; decreases the parasite burden of mice infected with L. tropica when administered at a dose of 50 mg/kg and 15 mg/kg, through intramuscular or intralesional routes, respectively; binds to the tRNA decoding A site of the 16S ribosomal RNA in bacteria; inhibits protein synthesis
Formal name: O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine, sulfate
Synonyms:
Molecular weight: 615.6
CAS: 1263-89-4
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Antibiotics|Aminoglycosides||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis
