A thiazide diuretic; inhibitor of carbonic anhydrase (CA); selective for CAII

Hydroflumethiazide – 50 mg

Brand:
Cayman
CAS:
135-09-1
Storage:
4
UN-No:
Non-Hazardous - /

Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA).{23242} It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 µM). Diuretics of the thiazide class, of which hydroflumethiazide is a member, inhibit the renal Na+/Cl- cotransporter.{37204} Formulations containing hydroflumethiazide have been used as diuretics.  

 

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SKU: 23612 - 50 mg Category:

Description

A thiazide diuretic; inhibitor of carbonic anhydrase (CA); selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 µM)

Formal name: 3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide

Synonyms:  NSC 44627

Molecular weight: 331.3

CAS: 135-09-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|Carbonic Anhydrase||Research Area|Cardiovascular System|Kidney & Renal Disease

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