An NK3 receptor antagonist; inhibits human liver microsomal CYP3A4/5 (apparent IC50s = 7.1 and 19.8 μM in midazolam 1'-hydroxylation and testosterone 6β-hydroxylation assays

MLE-4901 – 50 mg

Brand:
Cayman
CAS:
941690-55-7
Storage:
-20
UN-No:
Non-Hazardous - /

MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor.{51033} It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 μM in midazolam 1′-hydroxylation and testosterone 6β-hydroxylation assays, respectively.  

 

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SKU: 23587 - 50 mg Category:

Description

An NK3 receptor antagonist; inhibits human liver microsomal CYP3A4/5 (apparent IC50s = 7.1 and 19.8 μM in midazolam 1′-hydroxylation and testosterone 6β-hydroxylation assays, respectively)

Formal name: 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide

Synonyms:  AZD 2624|AZD 4901

Molecular weight: 459.6

CAS: 941690-55-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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