A benzamide analog that is used in PET applications; binds dopamine receptors (Kis = 0.95

Fluoroclebopride – 10 mg

Brand:
Cayman
CAS:
154540-49-5
Storage:
-20
UN-No:
Non-Hazardous - /

Fluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications.{36209,36205} It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays).{36208} It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively).{36206,36207} A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models.{36209,36205}  

 

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SKU: 23447 - 10 mg Category:

Description

A benzamide analog that is used in PET applications; binds dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2(long), D3, and D4 receptors, respectively); selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively); a fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models

Formal name: 4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-benzamide

Synonyms: 

Molecular weight: 391.9

CAS: 154540-49-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology||Research Area|Neuroscience

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