A PKD1 inhibitor (IC50 = 7 µM); also inhibits CAK and PLK1 but has no activity at AKT (IC50s = 8.4

CID797718 – 5 mg

Brand:
Cayman
CAS:
370586-05-3
Storage:
-20
UN-No:
Non-Hazardous - /

CID797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 µM).{25787} It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 µM, respectively). CID797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 µM. CID797718 is a byproduct in the synthesis of CID755673 (Item No. 15924).{32618}  

 

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SKU: 23428 - 5 mg Category:

Description

A PKD1 inhibitor (IC50 = 7 µM); also inhibits CAK and PLK1 but has no activity at AKT (IC50s = 8.4, 21.9, and >50 µM, respectively); inhibits PKD1 activity in LNCaP cells (IC50 = 0.21 µM); a byproduct in the synthesis of CID755673

Formal name: 1,2,3,4-tetrahydro-9-hydroxy-5H-[1]benzopyrano[3,4-b]pyridin-5-one

Synonyms: 

Molecular weight: 217.2

CAS: 370586-05-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|CDKs||Product Type|Biochemicals|Kinase Inhibitors|PKD & PKG||Product Type|Biochemicals|Kinase Inhibitors|Plks||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area

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