An antimycobacterial compound (MICs = 0.03-0.12 μg/ml against clinical isolates of M. paratuberculosis); has activity against 80 isolates of M. fortuitum

Clofazimine – 5 g

Brand:
Cayman
CAS:
2030-63-9
Storage:
-20
UN-No:
Non-Hazardous - /

Clofazimine is an antimycobacterial compound with MICs ranging from 0.03 to 0.12 μg/ml against clinical isolates of M. paratuberculosis.{36183} It also has activity against 80 isolates of M. fortuitum, M. chelonae, and M. fallax (MICs = ≤0.25-8 μg/ml).{36184} Clofazimine (25 mg/kg per day) reduces the number of M. tuberculosis infected cells in the spleen and lungs of mice infected with the multidrug-resistant clinical isolate strain CNL.{36185} Formulations containing clofazimine have been used for the treatment of leprosy and drug-resistant tuberculosis.  

 

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SKU: 23301 - 5 g Category:

Description

An antimycobacterial compound (MICs = 0.03-0.12 μg/ml against clinical isolates of M. paratuberculosis); has activity against 80 isolates of M. fortuitum, M. chelonae, and M. fallax (MICs = ≤0.25-8 μg/ml); reduces number of M. tuberculosis infected cells in the spleen and lungs of mice infected with the multidrug-resistant clinical isolate strain CNL

Formal name: N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine

Synonyms:  NSC 141046

Molecular weight: 473.4

CAS: 2030-63-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Leprosy||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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