A flavonol with antioxidant activity; increases cell viability of FeCl2 and H2O2-treated bmMSCs (1-100 µg/ml); scavenges PTIO radicals in a pH-dependent manner (IC50s = 2.6-0.4 mM for pH 5-9

(+)-Taxifolin – 100 mg

Brand:
Cayman
CAS:
480-18-2
Storage:
-20
UN-No:
Non-Hazardous - /

(+)-Taxifolin is a flavonol with antioxidant activity.{36570} It increases cell viability of FeCl2 and H2O2-treated bone marrow-derived mesenchymal stem cells (bmMSCs) when used at concentrations ranging from 1 to 100 µg/ml. It also scavenges PTIO radicals in a pH-dependent manner with lower concentrations needed at higher pH (IC50s = 2.6-0.4 mM for pH 5-9, respectively). (+)-Taxifolin protects against H2O2- and xanthine/xanthine oxidase-induced oxidative injury in primary cultured rat cortical cells (IC50 = 7.8 µg/ml) and inhibits lipid peroxidation in rat brain homogenates (IC50 = 1.02 µg/ml).{36571}  

 

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SKU: 23234 - 100 mg Category:

Description

A flavonol with antioxidant activity; increases cell viability of FeCl2 and H2O2-treated bmMSCs (1-100 µg/ml); scavenges PTIO radicals in a pH-dependent manner (IC50s = 2.6-0.4 mM for pH 5-9, respectively); protects against H2O2- and xanthine/xanthine oxidase-induced oxidative injury in primary cultured rat cortical cells (IC50 = 7.8 µg/ml); inhibits lipid peroxidation in rat brain homogenates (IC50 = 1.02 µg/ml)

Formal name: (2R,3R)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Synonyms:  (+)-Dihydroquercetin

Molecular weight: 304.3

CAS: 480-18-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Xanthine Oxidase

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