A mixture of glucocerebrosides isolated from soy; levels decrease during cold acclimatization in plants; involved in the regulation of virulence in fungi and act as elicitors in plants

Glucocerebrosides (Gaucher’s spleen) – 1 mg

Brand:
Cayman
CAS:
85305-87-9
Storage:
-20
UN-No:
Non-Hazardous - /

Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.{41133} They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species, where they comprise 5-30% of total lipids in the plant plasma membrane, and in fungi.{41133,41134,59454} Glucocerebroside levels decrease during cold acclimatization in plants and glucocerebrosides in fungi are involved in the regulation of virulence and act as elicitors in plants, stimulating plant defense mechanisms.{59454,59455} Glucocerebrosides are precursors in the synthesis of lactosylceramides and gangliosides. Increased levels of glucocerebrosides are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease.{41133,41135} This product is a mixture of glucocerebrosides, with variable ceramide chain lengths, isolated from the spleen of a human with Gaucher’s disease. [Matreya, LLC. Catalog No. 1057]  

 

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SKU: 23207 - 1 mg Category:

Description

A mixture of glucocerebrosides isolated from soy; levels decrease during cold acclimatization in plants; involved in the regulation of virulence in fungi and act as elicitors in plants, stimulating plant defense mechanisms; increased levels are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease

Formal name: 1-O-β-D-glucopyranosyl-ceramide

Synonyms:  Ganglioside GL1a|Gaucher cerebroside|GluCers (Gaucher’s spleen)|Glucosylceramides (Gaucher’s spleen)

Molecular weight: 812.3

CAS: 85305-87-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience||Research Area|Plant Biology|Plant Defense

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