A terpene with diverse biological activities; it inhibits DMPP-induced norepinephrine secretion and cytosolic calcium and sodium increases in chromaffin cells (IC50s = 70

(1R)-(+)-Camphor – 100 mg

Brand:
Cayman
CAS:
464-49-3
Storage:
-20
UN-No:
De Minimis - 2717 / 4.1

(1R)-(+)-Camphor is a terpene that has been found in C. sativa, C. indica, and C. sativa/C. indica hybrid strains as well as the essential oils from a variety of herbs including rosemary, lavender, and sage and has diverse biological activities.{42303,42305,42306,42307,42308,42304} It inhibits norepinephrine secretion and cytosolic calcium and sodium increases induced by the nicotinic acetylcholine receptor (nAChR) agonist 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively).{42305} (1R)-(+)-Camphor (65-260 μM) induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts.{42306} In vivo, (1R)-(+)-camphor increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice when administered at doses of 26 and 55 mM in drinking water post UV-exposure. It reduces cough frequency in citric acid-challenged guinea pigs.{42307} (1R)-(+)-Camphor is insecticidal, reducing digging activity and inducing mortality of fire ant workers.{42308} It has also been used as a building block in the synthesis of cannabinergic ligands.{42304}  

 

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SKU: 23175 - 100 mg Category:

Description

A terpene with diverse biological activities; it inhibits DMPP-induced norepinephrine secretion and cytosolic calcium and sodium increases in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively); induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts from 65-260 μM; increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice at 26 and 55 mM in drinking water post UV-exposure; reduces cough frequency in citric acid-challenged guinea pigs; reduces digging activity and induces mortality in fire ant workers; has been used as a building block in the synthesis of cannabinergic ligands

Formal name: (1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Synonyms:  (+)-Camphor|(R)-Camphor

Molecular weight: 152.2

CAS: 464-49-3

Purity: ≥98%

Formulation: A solid

Application||Product Type|Biochemicals|Natural Products|Phytocannabinoids||Product Type|Biochemicals|Pesticides||Research Area|Cell Biology|ECM & Adhesion Molecules||Research Area|Immunology & Inflammation

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