An AChE inhibitor (IC50 = 2.04 μM for human recombinant AChE); exhibits greater than 2

Cyclopenin – 5 mg

Brand:
Cayman
CAS:
20007-87-8
Storage:
-20
UN-No:
Non-Hazardous - /

Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC50 = 2.04 μM for human recombinant AChE) that is produced by Penicillium.{38326,38327,38328} It exhibits greater than 2,000-fold selectivity over recombinant equine butyrylcholinesterase with an IC50 value greater than 4,080 μM.{38325} Cyclopenin also has antibacterial activity against E. coli and M. pyogenes.{38326}  

 

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SKU: 23145 - 5 mg Category:

Description

An AChE inhibitor (IC50 = 2.04 μM for human recombinant AChE); exhibits greater than 2,000-fold selectivity over equine butyrylcholinesterase (IC50 = >4,080 μM)

Formal name: rel-(-)-4-methyl-3’S-phenyl-spiro[3H-1,4-benzodiazepine-3,2’R-oxirane]-2,5(1H,4H)-dione

Synonyms:  NSC 114538|NSC 604989

Molecular weight: 294.3

CAS: 20007-87-8

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Neuroscience

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