Albofungin – 1 mg

Brand:
Cayman
CAS:
37895-35-5
Storage:
-20
UN-No:
Non-Hazardous - /

Albofungin is a xanthone isolated from A. tumemacerans with diverse biological activities.{41087,41088} It inhibits the growth of various Gram-positive bacteria (MICs = 0.005-7.5 μg/ml), fungi (MICs = 0.0075-1.0 μg/ml), and mycobacteria (MICs = 1.0-10.0 μg/ml) with minimal activity against Gram-negative bacteria (MICs = ≥ 50.0 μg/ml).{41088,41090} At concentrations ranging from 0.005 to 0.01 μg/ml, albofungin is cytotoxic to HeLa cells.{41088} It also inhibits HIV reverse transcriptase with an IC50 value of 1 μM.{41089}  

 

Available on backorder

SKU: 23142 - 1 mg Category:

Description

A xanthone with diverse biological activities; inhibits growth of Gram-positive bacteria (MICs = 0.005-7.5 μg/ml), fungi (MICs = 0.0075-1.0 μg/ml), and mycobacteria (MICs = 1.0-10.0 μg/ml); cytotoxic to HeLa cells (0.005 to 0.01 μg/ml); inhibits HIV reverse transcriptase (IC50 = 1 μM)


Formal name: (1S,4R,8aR)-13-amino-3,4,8a,13-tetrahydro-1,15,16-trihydroxy-4-methoxy-12-methyl-1H-xantheno[4′,3′,2′:4,5][1,3]benzodioxino[7,6-g]isoquinoline-14,17(2H,9H)-dione

Synonyms:  Antibiotic P42-1|Antibiotic P42-C

Molecular weight: 520.5

CAS: 37895-35-5

Purity: ≥95%

Formulation: A solid


Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Antivirals|Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Reverse Transcriptases||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS