A pyrone isolated from S. pactum; selective and potent antimicrobial activity against H. pylori (MIC 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli

Actinopyrone A – 2.5 mg

Brand:
Cayman
CAS:
88378-59-0
Storage:
-20
UN-No:
Non-Hazardous - /

Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities.{41117} It has selective and potent antimicrobial activity against H. pylori (MIC = 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis.{41117,41118} Actinopyrone A also mildly inhibits growth of Gram-positive bacteria and dermatophytes with MIC values ranging from <6.25 to 25 μg/mL.{41117} Intravenous administration of actinopyrone A (30 μg/kg) increases coronary blood flow in dogs by 196.2%.  

 

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SKU: 23140 - 2.5 mg Category:

Description

A pyrone isolated from S. pactum; selective and potent antimicrobial activity against H. pylori (MIC 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis; intravenous administration (30 μg/kg) increases coronary blood flow in dogs by 196.2%

Formal name: 2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-6-methoxy-3,5-dimethyl-4H-pyran-4-one

Synonyms:  (+)-Actinopyrone A|SS 1538A

Molecular weight: 400.6

CAS: 88378-59-0

Purity: >95%

Formulation: An oil

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cardiovascular System|Vasculature||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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