Description
A riboside form of nicotinamide; a precursor of NAD+ and a source of vitamin B3; increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1,000 μM; decreases acetylation of FOXO1 and SOD2 but not tubulin; increases NAD+ levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day; increases NAD+ in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease,
Formal name: 3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium
Synonyms:
Molecular weight: 255.3
CAS: 1341-23-7
Purity: ≥95% Contains ~80% cyclodextrin as stabilizer
Formulation: A low melting semi-solid
Product Type|Biochemicals|Small Molecule Activators|Deacetylases||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease
