A fluorescent dye; ex/em spectra = 484/501 nm

3,3′-Dihexyloxacarbocyanine (iodide) – 1 g

Brand:
Cayman
CAS:
53213-82-4
Storage:
-20
UN-No:
Non-Hazardous - /

3,3′-Dihexyloxacarbocyanine (DiOC6(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively.{39274} At high concentrations, DiOC6(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, DiOC6(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis. DiOC6(3) can also be used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence.{39275,39276} DiOC6(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro.{39277}  

 

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SKU: 23124 - 1 g Category:

Description

A fluorescent dye; ex/em spectra = 484/501 nm, respectively; accumulates in ER at high concentrations and has been used to visualize ER in moss, yeast, and muscle cells; accumulates in mitochondria at low concntrations and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis; used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence; photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro,

Formal name: 3-hexyl-2-[3-(3-hexyl-2(3H)-benzoxazolylidene)-1-propen-1-yl]-benzoxazolium, iodide

Synonyms:  DiOC6(3)|NK 2280

Molecular weight: 572.5

CAS: 53213-82-4

Purity: ≥98%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Microtubule Dynamics||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking||Research Area|Cell Biology|Mitochondrial Biology

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