An adenosine analog; inhibits HCV replication in vitro (IC50 = 0.3 µM); converted intracellularly to adenosine triphosphate; inhibits growth of L. guyanensis in vitro (EC50 = 3 µM); eradicates L. guyanensis in vitro (10 µM)

2′-C-Methyladenosine – 50 mg

Brand:
Cayman
CAS:
15397-12-3
Storage:
-20
UN-No:
Non-Hazardous - /

2’-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 µM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 µM.{39652} It is converted intracellularly to adenosine triphosphate, which inhibits the RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). It also inhibits growth of L. guyanensis in vitro (EC50 = 3 µM) and eradicates it when used at a concentration of 10 µM.{39653}  

 

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SKU: 23062 - 50 mg Category:

Description

An adenosine analog; inhibits HCV replication in vitro (IC50 = 0.3 µM); converted intracellularly to adenosine triphosphate; inhibits growth of L. guyanensis in vitro (EC50 = 3 µM); eradicates L. guyanensis in vitro (10 µM)

Formal name: 2′-C-methyl-adenosine

Synonyms:  2-CMA

Molecular weight: 281.3

CAS: 15397-12-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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