An α1-AR agonist; topical application to the eyes or nasal mucosa activates of α1-ARs and induces vasoconstriction in rats; oral administration activates central α2-ARs resulting in respiratory depression and hypotension in rats and rabbits

Tetrahydrozoline (hydrochloride) – 10 g

Brand:
Cayman
CAS:
522-48-5
Storage:
4
UN-No:
Non-Hazardous - /

Tetrahydrozoline is an α1-adrenergic receptor (α1-AR) agonist.{41103} Topical application to the eyes or nasal mucosa activates α1-ARs and induces vasoconstriction in rats, while oral administration activates central α2-ARs resulting in respiratory depression and hypotension in rats and rabbits.{41103,41104,41105} Formulations containing tetrahydrozoline have been used to treat eye irritation and nasal congestion.{41103}  

 

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SKU: 23004 - 10 g Category:

Description

An α1-AR agonist; topical application to the eyes or nasal mucosa activates of α1-ARs and induces vasoconstriction in rats; oral administration activates central α2-ARs resulting in respiratory depression and hypotension in rats and rabbits

Formal name: 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole, monohydrochloride

Synonyms:  Tetryzoline

Molecular weight: 236.7

CAS: 522-48-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypotension||Research Area|Cardiovascular System|Vasculature|Vasoconstriction||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Ophthalmology

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