The primary metabolite of serotonin; formed when 5-HT is metabolized by monamine oxidase and aldehyde dehydrogenase in the liver; is excreted in urine; has been used as a biomarker for detection of neuroendocrine tumors; has been used as an internal standard for the quantification of serotonin metabolism in rat brain using mass spectrometry; associated with autism

5-hydroxy Indole-3-acetic Acid – 500 mg

Brand:
Cayman
CAS:
54-16-0
Storage:
-20
UN-No:
Non-Hazardous - /

5-hydroxy Indole-3-acetic acid (5-HIAA) is the primary metabolite of serotonin (5-HT; Item No. 14332).{40084} It is formed when 5-HT is metabolized by monamine oxidase and aldehyde dehydrogenase in the liver. 5-HIAA is excreted in urine and has been used as a biomarker for detection of neuroendocrine tumors and an internal standard for the quantification of serotonin metabolism in rat brain using mass spectrometry.{40085} 5-HIAA has also been associated with autism, insomnia, and chronic migraine.{40086,40087,40088}  

 

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Description

The primary metabolite of serotonin; formed when 5-HT is metabolized by monamine oxidase and aldehyde dehydrogenase in the liver; is excreted in urine; has been used as a biomarker for detection of neuroendocrine tumors; has been used as an internal standard for the quantification of serotonin metabolism in rat brain using mass spectrometry; associated with autism, insomnia, and chronic migraine

Formal name: 5-hydroxy-1H-indole-3-acetic acid

Synonyms:  5-HIAA|NSC 90432

Molecular weight: 191.2

CAS: 54-16-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cancer||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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