A sphingolipid and phytoceramide; used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro; in a healthy skin stratum corneum model

C24 Phytoceramide (t18:0/24:0) – 1 mg

Brand:
Cayman
CAS:
34437-74-6
Storage:
-20
UN-No:
Non-Hazardous - /

C24 Phytoceramide (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.{39255,39257,39256} C24 Phytoceramide (t18:0/24:0) is composed of a phytosphingosine (Item No. 20217) backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro.{39242,39254} In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytoceramide (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.{39258} [Matreya, LLC. Catalog No. 2036]  

 

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Description

A sphingolipid and phytoceramide; used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro; in a healthy skin stratum corneum model, permeability increases with incorporation of long-chain phytoceramides, such as C24 phytoceramide (t18:0/24:0)

Formal name: N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-tetracosanamide

Synonyms:  C24:0 Phytoceramide|Cer(t18:0/24:0)|Ceramide (t18:0/24:0)|N-Tetracosanoyl Phytosphingosine|N-Lignoceroyl Phytosphingosine

Molecular weight: 668.1

CAS: 34437-74-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Lipid Biochemistry|Sphingolipids

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